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011, 3-Pack - $0. Mobile Hydraulic hose replacement Newcastle. 009, 6-Pack - $0. 007 Shipping Shipping/Time to delivery 3-5 Business days Lab Tests Lab Testing Transparency Third Party Lab Tested post formulation for safety and potency, available on website Contaminants Contaminant-free Allergens Vegan and Gluten-free Refund policy Within 30 days Recommended for Patients who are looking for serious CBD oil support Countries served USA only (all 50 states) Why People Are Turning to CBD for Parkinson’s Disease Parkinson’s disease (PD) is a neurodegenerative disease characterized by low dopamine levels in the brain.

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Dopamine is a chemical that is responsible for managing a person’s movement and emotional responses - On-site Hydraulic hose Newcastle. Next to Alzheimer’s disease, PD is the second most prevalent degenerative disorder of the central nervous system(5). Currently, there is no absolute cure for Parkinson’s disease. The most common treatment is dopamine-replenishing medicines such as levodopa.

However, it is found to be less effective in treating non-motor symptoms of the disorder, especially in the late stage(6). According to the Parkinson’s Foundation, the disease’s non-motor symptoms include depression, anxiety, fatigue, sleep disorders, hallucinations, and vision problems(7). Long-term use of levodopa could also bring about side effects, such as low blood pressure, nausea, vomiting, lightheadedness, loss of appetite, confusion, and dyskinesia(8).

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Research has found that the use of levodopa early in one’s treatment increases one’s risk of developing dyskinesia(10). A 2010 study said that in extreme cases of levodopa-induced dyskinesia, the adverse effects may outweigh the benefits a patient gets from using the drug as a treatment. To avoid long-term motor complications in their patients, some doctors prescribe levodopa with caution and, if possible, as a second-line strategy in the treatment of Parkinson’s disease(11).

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CBD is the active ingredient of the cannabis plant that is non-psychoactive. The other primary component, tetrahydrocannabinol (THC), is the active ingredient in medical cannabis that can get people high. Research conducted in 2020 and published in the Journal of Psychopharmacology has found that CBD attenuated the anxiety and tremors of the test subjects who had PD(12).

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Those who took 300 mg of CBD before performing the speech had fewer reported symptoms than the placebo group. A placebo has no therapeutic effect and is often used in the control group of clinical experiments. Tremors and anxiety are symptoms of Parkinson’s disease. In the later stages of PD, patients could develop hallucinations and psychotic symptoms - Mobile Hydraulic hose Newcastle.

The researchers did not observe harmful side effects from the use of CBD. Another study has discovered marked improvements in the quality of life and well-being of test subjects who were administered with 300 mg of CBD daily, throughout the clinical test period(14). It is important to note that the test subjects had no psychiatric comorbidities (occurrence where a patient has overlapping medical conditions).

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In a study aimed at exploring the beneficial effects of CBD in treating Parkinson’s disease, the researchers initially gave five patients with dystonic movement disorders low doses of CBD(16). Over six weeks, the dosage of CBD was increased from 100 mg to 600 mg daily - Hydraulic hose repair Newcastle. The CBD products were given along with standard medications.

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Hypokinesia is characterized by no movement (akinesia) or slow movement (bradykinesia)(17). 24 hour On-site Hydraulic hose replacement near me Newcastle. It is a condition that impacts the motor function of patients with Parkinson’s disease and is caused by a disruption in the basal ganglia. Basal ganglia are nuclei found in the brain that are responsible for the coordination of movement.

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The study emphasizes that CBD could potentially be more effective as a preventive strategy. The challenge in preventive PD therapy is that it is difficult to diagnose the disease in its early stages. The researchers also underscore that, in most clinical trials, CBD is given to the test subjects who have already experienced a substantial progression of Parkinson’s disease.

According to a 2017 study, the manipulation of the endocannabinoid system (ECS) may have an essential role in the treatment of the symptoms of Parkinson’s disease(19). The ECS modulates several physiological functions, like mood, motor control, and cognition. The cannabinoid receptors of the ECS, particularly cannabinoid receptor 1, are abundant in the basal ganglia(20).

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One way to manipulate the ECS is through the introduction of laboratory-derived or medical marijuana-derived cannabinoids in the body. The primary cannabinoids that come from the marijuana plant (Cannabis Sativa) are CBD and THC. It has been suggested in the studies mentioned above that CBD might be helpful in the treatment of Parkinson’s disease.